HePoLLaboratories for Health Protection Research

Contact details:

Annemieke de Vries
Postbus 1, Bilthoven
+31 30 2743483

The RIVM Hepol laboratory has chemical- biological- molecular- and biochemical-laboratories with state of the art equipment and scientific methodologies to analyze and assess the risk of a broad range of products and substances for human health and the environment. Focus is on safety analysis of products, but also on health effects upon usage. In addition to this laboratory research, RIVM performs research to understand mechanisms that underlie adverse health effects. Moreover RIVM develops alternatives for animal testing. This laboratory infrastructure is used for: - Crisis or incident management: identification of risks, and assessment of effects on human health - Reference tasks - Research and innovation

ยท RIVM offers a state of the art laboratory infrastructure for research or for instance during crisis or incidents. The laboratory infrastructure has an efficient design and the staff has broad knowledge and skills. A main part of the infrastructure is accredited ISO17025), and the laboratory research is performed under strict levels of confidentiality. RIVM works alongside external partners to ensure maximum efficiency in the use of resources and expertise while safeguarding its independence. It is actively involved in the standardization programmes at national (NEN), European (CEN) and international (ISO) levels, as member or chair of committees or workgroups. In 2018 RIVM will relocate to its new premises in Utrecht Science Park and create a centralized, shared laboratory facility . Main lines of research for which the laboratory infrastructure is used:
- Analysis of composition of pharmaceuticals, tobacco products, drugs and illegal medicines, vaccines, blood products, food supplements and, medical devices with the aim of identifying possible risks for the user.
- Analysis of health effects of such products using in vitro and in vivo test models, including general molecular biology, OMICS techniques and, biochemistry.
- Research in animal models and human cohort studies with focus on the effects of lifestyle - e.g. nutrition, 24 hrs economy, factors accelerating ageing - on human health and disease.
- Development of novel and/or innovative methods in the above mentions lines of research.
- Development of alternatives for animal testing in the field of toxicology.

Connection to strategic developments
Life Sciences & Health
Health and Food