Cohort studies, bio banks and databases Cohort studies, bio banks and databases

Contact details:

Rob Riesmeijer en Jantiene Schuit
Postbus 1, Bilthoven

RIVM manages several cohort studies, biobanks and databases and performs surveys related to health. These studies and collections are unique and essential for RIVM’s knowledge of the health determinants. The more than 100.000 samples and numerous data bases of these studies and collections are crucial for the knowledge base of RIVM. Cohort studies that have started in the 80’s such as the PPHVZ (hart and coronary disease cohort) have been extended with new diseases such as cancer, diabetes, COPD and ageing have been integrated with cohort studies such as MORGEN and Doetinchem (see below), and provide a wealth of data. These data provide a unique insight into the causes of diseases and ageing and enable experts to develop evidence based interventions. RIVM also investigates the relationship between for and health using the Food Consumption survey. The Food Consumption Survey contributes to policy development for healthy and safe food, for product information, education and food research. The Food Consumption Survey (FCS) is a monitoring system based on three different modules. The data provide a thorough understanding of food consumption and the nutritional status of specific groups or of the Dutch citizens as a whole and provide insight into food consumption, the intake of macro and micro food constituents and the intake of potential harmful chemical substances. Data about food, food composition and nutritional values can be accessed on line through the NEVO (Nederlands Voedingstoffenbestand) website.

The cohort studies, biobanks and databases provide a unique collection of samples and data collected sometimes for more than 20 years of specific groups of the Dutch population that can be used for numerous studies within RIVM or they could be used for studies by others such as universities or national or international knowledge institutes. Below a number of cohort studies / databases is shortly described:
• PIENTER (database and biobank); the aim of these studies is to gain insight into how well the Dutch population is protected against vaccine-preventable diseases through the national immunization program (NIP). Size 18.000 samples/individuals
• PIAMA; Birth cohort, studies biological markers in children; sixe 3500 samples/individuals (owned by IRAS and RIVM)
• PPHVZ; Studies life style and risk factors for diseases; size 36.000 samples/individuals
• MORGEN; Studies life style factor and chronic diseases; size 22.000 samples/individuals (part of EU EPIC study)
• Doetinchem; Studies life style and risk factors on chronic diseases; size: (round 3) 4900, (round 4) 4500, (round 5) 4000 samples/individuals
• Food Consumption Survey; Studies food consumption patterns and composition and nutritional value of food
• Human Clinical Studies; monitors the national vaccination programme; size 30.000 samples/individuals
• Several databases on infectious diseases; ISIS-AR (antimicrobial resistance), PREZIES (healthcare-associated infections in hospitals), SNIV (healthcare-associated infections in nursing homes), OSIRIS (notifiable infectious diseases), Praeventis (registration database of the NIP).

Connection to strategic developments
Life Sciences & Health
Health and Food